Nanoretinol^® is a water-based, gel-like formulation. Its texture is light and non-greasy, making it suitable for all skin types, including oily and combination skin. Despite its lightweight texture, Nanoretinol^® deeply hydrates and nourishes the skin. This is because as the nanoparticles release their retinol content, the skin cells gradually absorb the phospholipid (natural lipids) contained in the nanoparticles' membranes. This unique process allows for deep nourishment without leaving a heavy or oily residue, making Nanoretinol^® an excellent choice for all skin types.
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Essentially, the application of Nanoretinol^® in your nighttime routine results in complete absorption by your skin, leaving it with a smooth, matte finish. Upon waking up, you'll be greeted by skin that feels deeply moisturized and richly nourished.

While it's true that retinol is typically lipid-soluble, the unique formulation of Nanoretinol^® allows it to be part of a water-based serum. The retinol in Nanoretinol^® is not dissolved in the water base. Instead, it is encapsulated within nanoscopic particles that protect and preserve it.

These nanoparticles are negatively charged, causing them to repel each other. This repulsion forms a three-dimensional mesh of nanoparticles that are evenly distributed throughout Nanoretinol^®. This innovative structure ensures a homogeneous distribution of retinol, allowing for consistent application and absorption across your skin.

Nanoretinol^® stands alone as the only water-based serum in the market harnessing this advanced technology, setting a new standard in skincare innovation.

Nanoretinol^® contains 0.2% of fully stabilized and protected retinol. Yet, due to its encapsulation within biomimetic nanoparticles, you should expect it to be significantly different from any traditional retinol at this concentration.
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On the one hand, the results of Nanoretinol^® will be drastically superior to a retinol product with the same concentration, as outlined in our scientific study. On the other hand, the side effects (redness, irritation, peeling) will tend to be much lower, according to the data from our in vivo testing on humans.

Nanoretinol^® is engineered to significantly reduce the irritation and redness typically associated with retinol use. However, if you have sensitive, atopic skin, or any other skin condition, it's advisable to seek a dermatologist's guidance before incorporating Nanoretinol^® into your skincare routine.

While Nanoretinol^® is generally compatible with other skincare products, it's important to be aware of certain ingredients that may interact with it. Avoid using Nanoretinol^® simultaneously with benzoyl peroxide, as it can oxidize retinoids and reduce their effectiveness. Similarly, alpha and beta hydroxy acids (AHAs and BHAs), such as glycolic acid, lactic acid, and salicylic acid, can increase skin sensitivity and may cause irritation when used with retinoids.
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Vitamin C, while beneficial for the skin, is best used at a different time of day than retinoids. Typically, Vitamin C is most effective in the morning, while retinoids, including Nanoretinol^®, are recommended for nighttime use.
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Lastly, avoid using physical and chemical exfoliants while using retinoids, as this can lead to over-exfoliation, causing dryness, redness, and irritation.

It's not recommended to use both Nanoretinol^® and Tretinoin on the same day, as Nanoretinol^® may increase the side effects of Tretinoin. We strongly advise consulting a healthcare professional before using the two products together, as Tretinoin is a prescription drug that can cause severe side effects if used incorrectly.

However, if you leave a prudential time between the use of Tretinoin and Nanoretinol^® (at least 24 hours), we believe that they can complement each other exceptionally well. Tretinoin primarily acts on the superficial layers of the skin, while Nanoretinol^® targets the deeper layers, thanks to the biomimetic nanoparticles it employs.

Using both products can offer a comprehensive skincare solution, with Nanoretinol^® focusing on deeper wrinkles and structural weaknesses, and Tretinoin improving texture and addressing more superficial fine lines.

For optimal results with Nanoretinol^®, it's best to incorporate it into your nighttime skincare routine. After thoroughly cleansing your face, apply Nanoretinol^® as the first step before introducing any other cosmetic products. This ensures that Nanoretinol^® is able to deeply penetrate your skin, maximizing its rejuvenating effects.

The timeline for seeing results with Nanoretinol^® can vary greatly depending on several factors, including age, genetics, and lifestyle habits. Remarkably, changes related to skin texture and hydration can often be detected within just a few days. This swift improvement is attributed to the nourishing and restorative effects of the phospholipids that constitute the external shell of the nanoparticles. These phospholipids are readily utilized by skin cell membranes as nourishment, enhancing the overall health and vitality of the skin.

In most instances, initial improvements may be observed within weeks of starting the product. The surge in collagen and elastin production begins within days of using Nanoretinol^®. However, while the production of these vital proteins starts early, structural changes in the skin, which are more noticeable and transformative, typically become apparent after between 2 and 3 months of consistent use.

In our clinical trial on humans, participants experienced structural changes in their skin with a 61% increase in firmness and a 56% increase in elasticity, in just 56 days of continuous use of Nanoretinol^®.
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However, for optimal results, a commitment to using Nanoretinol^® for a period of 6 to 12 months is recommended. This duration ensures the product has ample time to work on the deeper layers of the skin, leading to more significant and lasting changes in the skin's appearance.

It's important to remember that everyone's skin is unique, and individual results may vary. Consistent use and patience are key when it comes to seeing the full benefits of any skincare product, including Nanoretinol^®.